Determining The Risk Factors of Post-Menopausal Bleeding: A Cross-Sectional Study
DOI:
https://doi.org/10.69980/ajpr.v28i1.117Keywords:
Post-menopausal bleeding, risk factors, screening, obesity, metabolic disordersAbstract
Introduction
Post-menopausal bleeding (PMB) is a significant clinical symptom that warrants thorough evaluation due to its potential association with malignancies. This study aims to assess the socio-demographic, reproductive, and medical risk factors linked to PMB among post-menopausal women attending a tertiary care hospital in Chennai, India.
Methodology
A cross-sectional study was conducted among 50 post-menopausal women aged over 50 years. Data were collected using structured interviews and medical records. Parameters such as age, BMI, education, employment, parity, menstrual hygiene, chronic conditions, reproductive infections, and Pap smear screening history were analyzed.
Results
The majority of participants (50%) were aged 50–59 years, with 64% being literate. A significant proportion (46%) were overweight or obese, and 60% had Type 2 Diabetes Mellitus. High parity (≥4 full-term pregnancies) was observed in 80% of participants. A concerning 60% reported frequent reproductive infections, and only 60% had undergone Pap smear screening. PMB occurrence was highest within the first-year post-menopause, with 40% reporting a family history of the condition.
Conclusion
This study highlights obesity, metabolic disorders, high parity, and inadequate screening as key risk factors for PMB. The findings underscore the need for targeted awareness programs, improved healthcare accessibility, and enhanced screening efforts to facilitate early detection and management. Future research should explore longitudinal data to better understand PMB's etiology and prevention strategies.
References
1. Brand AH. The woman with postmenopausal bleeding. Australian family physician. 2007 Mar;36(3).
2. Astrup K, Olivarius ND. Frequency of spontaneously occurring postmenopausal bleeding in the general population. Acta obstetricia et gynecologica Scandinavica. 2004 Jan 1;83(2):203-7.
3. Dawood NS, Peter K, Ibrar F, Dawood A. Postmenopausal bleeding: causes and risk of genital tract malignancy. Journal of Ayub Medical College Abbottabad. 2010 Jun 1;22(2):117-20.
4. Moodley M, Roberts C. Clinical pathway for the evaluation of postmenopausal bleeding with an emphasis on endometrial cancer detection. Journal of Obstetrics and Gynaecology. 2004 Jan 1;24(7):736-41.
5. Mallick A, Behera R, Subudhi K. Histopathological study of endometrium in postmenopausal bleeding. Journal of Evolution of Medical and Dental Sciences. 2013 Nov 18;2(46):9010-9.
6. Battista RN, Grover SA. Early detection of cancer: an overview. Annual review of public health. 1988 May;9(1):21-45.
7. Smith RA, von Eschenbach AC, Wender R, Levin B, Byers T, Rothenberger D, Brooks D, Creasman W, Cohen C, Runowicz C, Saslow D. American Cancer Society guidelines for the early detection of cancer: update of early detection guidelines for prostate, colorectal, and endometrial cancers: Also: update 2001—testing for early lung cancer detection. CA: a cancer journal for clinicians. 2001 Jan;51(1):38-75.
8. Ashworth P, Whelan E. Postmenopausal bleeding and endometrial cancer. InnovAiT. 2016 Nov;9(11):656-62.
9. Mittra I, Mishra GA, Singh S, Aranke S, Notani P, Badwe R, Miller AB, Daniel EE, Gupta S, Uplap P, Thakur MH. A cluster randomized, controlled trial of breast and cervix cancer screening in Mumbai, India: methodology and interim results after three rounds of screening. International journal of cancer. 2010 Feb 15;126(4):976-84.
10. Aswathy S, Quereshi MA, Kurian B, Leelamoni K. Cervical cancer screening: Current knowledge & practice among women in a rural population of Kerala, India. Indian Journal of Medical Research. 2012 Aug 1;136(2):205-10.
11. Sindhuri R, Dongre AR. Postmenopausal bleeding among rural women in Tamil Nadu, India: Mixed methods study. Indian journal of community medicine. 2018 Oct 1;43(4):288-93.
12. Smith RA, Andrews KS, Brooks D, Fedewa SA, Manassaram-Baptiste D, Saslow D, et al. Cancer screening in the United States. CA Cancer J Clin. 2019;69(1):27-41.
13. Kaaks R, Lukanova A, Kurzer MS. Obesity, endogenous hormones, and endometrial cancer risk. Cancer Epidemiol Biomarkers Prev. 2002;11(12):1531-43.
14. Mittra I, Mishra GA, Singh S, et al. A population-based screening program for early detection of common cancers in Mumbai, India. Bull World Health Organ. 2010;88(3):180-7.
15. Dossus L, Allen N, Kaaks R, Bakken K, Lund E, Tjonneland A, et al. Reproductive risk factors and endometrial cancer: the European prospective investigation into cancer and nutrition. Int J Cancer. 2010;127(2):442-51.
16. Parazzini F, La Vecchia C, Bocciolone L, Franceschi S. The epidemiology of endometrial cancer. Gynecol Oncol. 1991;41(1):1-16.
17. Berek JS, Novak E. Berek & Novak’s gynecology. 15th ed. Philadelphia: Lippincott Williams & Wilkins; 2012.
18. Sankaranarayanan R, Thara S, Esmy PO, Basu P. Cervical cancer: screening and prevention. Curr Opin Obstet Gynecol. 2008;20(1):58-64.
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