Impact Of Drug Therapy And Healthcare Practices On Functional Outcomes And Quality Of Life In COPD Patients: A Real-World Indian Perspective

Abstract

Background: Chronic Obstructive Pulmonary Disease (COPD) imposes significant limitations on patients’ quality of life (QoL) and functionality. This study assesses the impact of pharmacotherapy and healthcare practices on treatment adherence, functional status, and perceived QoL among COPD patients in a tertiary care setting.

Methods: This cross-sectional study was conducted from January 2021 to July 2022 on 612 diagnosed COPD patients. Patient demographics, occupational exposure, indoor and outdoor pollution, treatment adherence, and functional capacity were recorded. QoL was assessed based on symptom burden and daily activity limitation.

Results: Most patients were male (82.2%) and aged between 51–65 years. More than 40% reported moderate to severe limitation in routine activities. Suboptimal adherence to inhalational therapy was seen in 41.5%, attributed to cost and lack of education. Women exposed to indoor smoke reported significantly worse symptoms. There was a clear correlation between guideline-based therapy and improved functional scores.

Conclusion: In COPD patients, the integration of rational pharmacotherapy with patient education significantly improves functional capacity and quality of life. Special attention must be paid to vulnerable populations such as elderly women exposed to indoor air pollutants.