Hyperbaric Oxygen Therapy: A Comprehensive Literature Review Of Mechanisms, Clinical Indications, And Emerging Applications

Authors

  • Dr. Renny Justine.
  • Dr. Chandra Shekhar Mohanty
  • Dr. Subranshu Kumar
  • Dr. Divya Singh

DOI:

https://doi.org/10.69980/ajpr.v28i5.489

Keywords:

Hyperbaric oxygen therapy, decompression sickness, wound healing, neurological injury, chronic wounds, radiation induced soft tissue injuries, clinical indications, emerging applications.

Abstract

Hyperbaric oxygen therapy (HBOT) delivers 100% oxygen at pressures above atmospheric level to enhance tissue oxygenation. It has established efficacy in specific conditions such as decompression sickness, carbon monoxide poisoning, and radiation-induced tissue injury. Increasing evidence suggests its potential benefits in neurological injuries and chronic wounds. This review summarises the physiological basis of HBOT, approved indications, emerging clinical uses, safety considerations and current challenges, providing an updated synthesis for clinicians and researchers involved in hyperbaric medicine.

Author Biographies

Dr. Renny Justine.

Junior Resident, Department of Marine Medicine, INHS Asvini Mumbai.

Dr. Chandra Shekhar Mohanty

HOD and Professor, Classified Specialist, Department of Marine Medicine, INHS Asvini Mumbai.

Dr. Subranshu Kumar

Senior Resident and Graded Specialist, Department of Marine Medicine, INHS Asvini Mumbai.

Dr. Divya Singh

Junior Resident, Department of Marine Medicine, INHS Asvini Mumbai.

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Published

2025-06-29