Retrospective evaluation of Transfusion Transmissible infections in Discarded Blood Units: A 5-year analysis from a regional Blood Centre at Bundi, Rajasthan

Authors

  • Dr. Manu Jethalya
  • Dr Saurabh Totla
  • Dr. Neil Sharma

DOI:

https://doi.org/10.69980/ajpr.v28i5.541

Keywords:

Blood Safety Transfusion-Transmissible Infections, HIV, HCV, HBsAg, VDRL, Malaria, Blood Bank, Rajasthan, India.

Abstract

This study retrospectively analyses data on discarded blood units due to positivity for Transfusion-Transmissible infections (TTIs) at Regional Blood Centre of Pt. B.S. Sharma General Hospital, Bundi, Rajasthan, from January 2020 to December 2024. The objective was to determine the prevalence and trends of HIV, HCV, HBsAg, VDRL (syphilis), and Malarial Parasite (M.P.) among discarded donated blood units. Data were sourced from the Blood Centre annual discard reports. Over the five years, a total of 38,678 blood units were collected, with 1,031 units (2.67%) discarded due to TTI positivity. Hepatitis B surface antigen (HBsAg) was the most common reason for discarding units, accounting for 825 discard units (80.02%of all discards, 2.13% of total collections). The number of HIV-positive discards were 32, HCV was 37, VDRL was 134, and Malaria Parasite was 3. This emphasizes the critical need for robust and sustained screening protocols, while also identifying key areas for focused public health interventions to lower the burden of transfusion-transmitted infections (TTIs) in the donor population. These efforts are in alignment with both national and global strategies aimed at ensuring the highest standards of blood safety.

Author Biographies

Dr. Manu Jethalya

Assistant professor, department Pathology, Government Medical College, Bundi

Dr Saurabh Totla

Consultant Radiologist, Kota

Dr. Neil Sharma

Associate professor, department Pathology, Government Medical College, Alwar.

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Published

2025-07-26