Phytochemical Screening and Antimicrobial Activity of Schweinfurthia papilionacea (L.) BOISS
DOI:
https://doi.org/10.69980/ajpr.v28i5.636Keywords:
antibacterial, antifungal, chloroform extract, methanol extract, phytochemicalsAbstract
The aim of this study was to evaluate the antimicrobial activity of methanol and chloroform extracts of Schweinfurthia papilionacea against various microbial strains, including Pseudomonas aeruginosa, Staphylococcus aureus, Shigella flexneri, Escherichia coli, Salmonella typhi, and Aspergillus flavus. The phytochemical analysis of the extracts revealed a rich composition of bioactive compounds, including saponins, alkaloids, flavonoids, and phenolic compounds. The concentrations of the phytochemicals in the samples were varied, ranging from 0.2 to 0.5 mg/ml, and the concentrations ranged from 10.3 to 16.4 mm. Methanol extracts demonstrated varying degrees of effectiveness, with inhibition zones for 50 ml concentrations varying from 8.61.28 to 16.52.56 mm, and for 75 mL concentrations from 12.32.45 to 24.32.63 mm for 50 mg and 75 mg, respectively. Both extracts exhibited dose-dependent antibacterial activity, with higher concentrations generally resulting in larger inhibition zones. The results suggest that both aqueous extracts have the potential to inhibit fungal growth, with both extracts showing greater potency at lower concentrations.
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