Prevalence and Antimicrobial Resistance Pattern of Staphylococcus aureus in the Kanpur Nagar.
DOI:
https://doi.org/10.69980/ajpr.v28i5.647Keywords:
Staphylococcus aureus, MRSA, antimicrobial resistance, Kanpur Nagar, prevalence, antibiotic sensitivityAbstract
Background: Staphylococcus aureus is a significant human pathogen responsible for a range of infections, with increasing concern due to rising antimicrobial resistance, particularly Methicillin-Resistant S. aureus (MRSA). This study aimed to determine the prevalence and antimicrobial resistance pattern of S. aureus in Kanpur Nagar.
Methods: A total of 309 clinical samples were collected from patients across various healthcare settings. Isolation and identification of S. aureus were performed using standard microbiological methods. Antimicrobial susceptibility testing was conducted using the Kirby-Bauer disc diffusion method following CLSI guidelines.
Results: The overall prevalence of S. aureus was 15.7%, with the highest recovery from nasal swabs, pus/wound samples, and throat swabs. MRSA was present across all age groups, most commonly in the 25–44 age group, though no significant association with age or gender was found. Antibiotic sensitivity was highest to vancomycin (86%), linezolid (79%), and gentamicin (70.6%), while penicillin (5.3%) and ampicillin (16%) showed high resistance levels.
Conclusion: The findings indicate a moderate burden of S. aureus in the region, with notable resistance to first-line antibiotics. Regular antimicrobial surveillance, judicious antibiotic use, and strict infection control policies are essential to limit the spread of MRSA and other resistant strains.
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