Clinical Evaluation of Vishmusthyadi vati and kalyank churna in the withdrawal of tobacco chewing addiction: a case study

Abstract

Smokeless tobacco (ST) chewing addiction represents a substantial public health burden, particularly in India, necessitating effective withdrawal strategies. In Ayurveda, tobacco (Tamraparna or Nicotiana tabacum) is classified as a Sthavara Vanaspatij Visha (immobile plant poison). Chronic use and subsequent withdrawal induce a neurobehavioral syndrome characterized by the vitiation of Vata and Kapha Doshas and disturbance of the Manovaha Srotas. This report details the outcome of an Ayurvedic combined therapeutic regimen targeting this withdrawal pathology.[i],

Case Presentation

A 25-year-old male labourer, presented with a 5-to-6-year history of daily smokeless tobacco (Zarda) addiction. Initial assessment using the Nicotine Withdrawal Scale for Tobacco Chewing Addiction yielded a total score of 24, classifying the patient as suffering from Severe Withdrawal. Primary complaints included severe craving, anxiety, irritability, and difficulty in concentration.

Intervention

The patient was administered a combined regimen for a continuous period of 21 days as per the research protocol. The intervention comprised Vishmusthyadi Vati (1–2 Vati, orally, twice daily with lukewarm water after meals) and Kalyank Churna (3g, four times daily, administered specifically for chewing).

Results

Subjective clinical efficacy was highly significant. The total Nicotine Withdrawal Score decreased substantially from 24 (Severe) at baseline to 7 (Mild) at the end of the 21-day intervention, representing a 70.83% improvement in symptomatic relief. The primary end point patient unwillingness to consume tobacco was achieved. Objective assessments revealed metabolic shifts typical of the acute cessation phase, including increases in Total Cholesterol (120.9 to 152.2) and Triglycerides (111.6 to 131.2). Hematological markers (ESR, TLC) showed favorable minor reductions.

Conclusion

The synergistic application of the nervine tonic and antitoxic Vishmusthyadi Vati alongside the Deepana-Pachana and behavioral substitution agent Kalyank Churna proved highly effective in managing acute tobacco withdrawal symptoms. The regimen addresses both the Visha effects and the associated Vata-Kapha pathology. The results indicate a successful cessation strategy, though they mandate continued metabolic monitoring in the post-cessation phase.