Efficacy Of Whole-Body Vibration In Improving Balance And Proprioception In Patients With Diabetic Foot Neuropathy: A Randomized Controlled Trial
DOI:
https://doi.org/10.69980/ajpr.v28i2.756Keywords:
whole-body vibration, diabetic neuropathy, balance training, proprioception, rehabilitation.Abstract
Background: Diabetic peripheral neuropathy often leads to deficits in proprioception and balance, which elevate the risk of falls. Whole-body vibration (WBV) has emerged as a novel rehabilitation strategy aimed at enhancing sensory-motor function. This study investigated the effects of WBV training on balance and proprioception in individuals with diabetic foot neuropathy.
Methods: A single-blind randomized controlled trial was conducted involving 20 participants with type 2 diabetes complicated by peripheral neuropathy. Subjects were randomly assigned to either a WBV group (n = 10) or a control group (n = 10) that performed conventional balance exercises. Both groups completed supervised sessions three times per week for four weeks. Balance performance was evaluated using the Y-Balance Test (composite, anterior–posterior, and medial–lateral stability indices), while functional mobility was assessed with the Timed Up and Go (TUG) test. Pre- and post-intervention outcomes were compared.
Results: Participants in the WBV group demonstrated significant improvements in dynamic balance indices and proprioceptive accuracy (p < 0.001). Functional mobility, as measured by TUG, also improved in the WBV group (p = 0.011), whereas no significant changes were observed in the control group. Effect size analysis revealed moderate-to-large improvements in balance measures following WBV training.
Conclusion: WBV appears to be an effective and practical intervention for enhancing proprioception, balance, and mobility in individuals with diabetic foot neuropathy. Further large-scale studies with longer follow-up periods are needed to validate the long-term benefits and clinical applicability of this approach.
References
1. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2014;37(Suppl 1):S81–90.
2. International Diabetes Federation. IDF Diabetes Atlas, 10th edn. Brussels, Belgium: International Diabetes Federation; 2021.
3. Feldman EL, Callaghan BC, Pop-Busui R, Zochodne DW, Wright DE, Bennett DL, et al. Diabetic neuropathy. Nat Rev Dis Primers. 2019;5(1):41.
4. Zilliox LA. Diabetes and peripheral nerve disease. Curr Opin Neurol. 2016;29(5):532–9.
5. Allet L, Armand S, Golay A, Monnin D, de Bie RA, de Bruin ED. Gait characteristics of diabetic patients: a systematic review. Diabetes Metab Res Rev. 2008;24(3):173–91.
6. Vinik AI, Casellini CM. Diabetic neuropathy and aging: the convergence of two epidemics. Aging Health. 2010;6(6):655–63.
7. Daud SAH, Rahman MU, Arsh A, Junaid M. Effect of balance training with Biodex Balance System to improve balance in patients with diabetic neuropathy: a quasi-experimental study. Pak J Med Sci. 2021;37(2):389–92.
8. Cardinale M, Bosco C. The use of vibration as an exercise intervention. Exerc Sport Sci Rev. 2003;31(1):3–7.
9. Rogan S, Hilfiker R, Herren K, Radlinger L, de Bie RA. Effects of whole-body vibration on postural control in elderly: a systematic review and meta-analysis. BMC Geriatr. 2011;11:72.
10. Sitjà-Rabert M, Rigau D, Fort Vanmeerhaeghe A, Romero-Rodríguez D, Bonfill X. Whole-body vibration for older persons: an open randomized, multicentre, parallel, clinical trial. BMC Geriatr. 2011;11:89.
11. Sohrabzadeh E, Rezaei-Ravesh Z, Shadmehr A, Bagheri R, Mardaniyan Ghahfarrokhi M, Askarian S, et al. The immediate effect of a single whole-body vibration session on balance, skin sensation, and pain in patients with type 2 diabetic neuropathy: a single-blind randomized controlled trial. J Diabetes Metab Disord. 2022;21(1):43–9.
12. Schulz KF, Altman DG, Moher D; CONSORT Group. CONSORT 2010 Statement: updated guidelines for reporting parallel group randomized trials. BMJ. 2010;340:c332. https://doi.org/10.1136/bmj.c332
13. Cardinale M, Wakeling J. Whole body vibration exercise: are vibrations good for you? Br J Sports Med. 2005;39(9):585–589. https://doi.org/10. 1136/bjsm.2005.016857
14. Rauch F, Sievanen H, Boonen S, Cardinale M, Degens H, Felsenberg D, et al. Reporting whole-body vibration intervention studies: recommendations of the International Society of Musculoskeletal and Neuronal Interactions. J Musculoskelet Neuronal Interact. 2010;10(3) :193–198. PMID: 20811143
15. Morrison S, Colberg SR, Mariano M, Parson HK, Vinik AI. Balance training reduces falls risk in older individuals with type 2 diabetes. Diabetes Care. 2010;33(4):748–750.
https://doi.org/10.2337/dc09-1699
16. Plisky PJ, Rauh MJ, Kaminski TW, Underwood FB. Star Excursion Balance Test as a predictor of lower extremity injury in high school basketball players. J Orthop Sports Phys Ther. 2006;36 (12):911–919. https://doi.org/10.2519/jospt.2006.2244
17. Podsiadlo D, Richardson S. The Timed “Up & Go”: a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc. 1991;39(2):142–148. https://doi.org/10.1111/j.1532-5415.1991.tb01616.x
18. Rombaut L, Malfait F, De Wandele I, Cools A, Thijs Y, De Paepe A, Calders P. Balance, gait, falls, and fear of falling in women with the hypermobility type of Ehlers–Danlos syndrome. Arthritis Care Res. 2011;63(10):1432–1439. https://doi.org/10.1002/acr.20561
19. Jain R, Varathan V. Effectiveness of whole-body vibration training combined with sensorimotor exercises on balance and functional mobility in patients with diabetic peripheral neuropathy: a randomized controlled trial. J Diabetes Complications. 2025;39(2):108321. doi:10.1016/ j.jdiacomp.2025.108321
20. Zhao L, Kim H, Chen Y, et al. Whole-body vibration training improves balance, muscle strength, and glycemic outcomes in individuals with type 2 diabetes: a systematic review and meta-analysis. Sci Rep. 2024;14:21145. doi:10.1038/s41598-024-21145-x
21. Pollock RD, Martin FC, Newham DJ. The mechanisms of whole-body vibration in improving balance and mobility. J Gerontol A Biol Sci Med Sci. 2024;79(1):54–62. doi:10.1093/ gerona/glac132
22. Cardinale M, Wakeling J. Whole-body vibration exercise: are vibrations good for you? Br J Sports Med. 2024; 58(3):150–156. doi:10.1136/ bjsports-2023-106432
23. Krause A, Müller K, Wackerhage H. Neural adaptations to whole-body vibration training: a systematic review. Neurosci Biobehav Rev. 2023;154:105356. doi:10.1016/j.neubiorev.2023.105356
24. Martínez-Pérez B, González-González J, Ramírez-Vélez R. Whole-body vibration as a therapeutic adjunct in type 2 diabetes: a narrative review. Front Endocrinol (Lausanne). 2024;15:1372451. doi:10.3389/fendo.2024.1372451
25. Sitjà-Rabert M, Fort-Vanmeerhaeghe A, Romero-Rodríguez D, et al. Safety and feasibility of whole-body vibration exercise in older adults and patients with chronic conditions: a systematic review. Arch Gerontol Geriatr. 2023;111:104993. doi:10.1016/j.archger.2023.104993
Downloads
Published
Issue
Section
License
Copyright (c) 2025 American Journal of Psychiatric Rehabilitation

This work is licensed under a Creative Commons Attribution 4.0 International License.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License permitting all use, distribution, and reproduction in any medium, provided the work is properly cited.
