Efficacy Of Maha Agad In The Management Of Dushi Visha Janya Artava Kshaya (Polycystic Ovarian Syndrome): A Clinical And Pharmacological Investigation
DOI:
https://doi.org/10.69980/ajpr.v29i1.880Keywords:
Ayurveda, PCOS, Dushi Visha Janya Artava Kshaya.,Ayurveda, Agadtantra, InfertilityAbstract
The maintenance of a rhythmic and healthy menstrual cycle serves as a foundational pillar for the physiological, psychological, and reproductive well-being of women, acting as a critical determinant for the health of future generations. Polycystic Ovarian Syndrome (PCOS) has emerged as a pervasive, multi-factorial endocrine disorder affecting women globally, characterized by a complex interplay of hormonal imbalances and metabolic dysfunctions. Historically identified through the Stein-Leventhal triad comprising oligomenorrhea, hirsutism, and obesity contemporary diagnostic frameworks such as the Rotterdam criteria (2003) now define the syndrome through the presence of at least two of three markers: oligo-ovulation or anovulation, clinical or biochemical hyperandrogenism, and polycystic ovarian morphology observed via ultrasonography.
From an Ayurvedic perspective, while PCOS is not described as a singular disease entity in classical texts, its clinical manifestations align closely with the pathological state of Artava Kshaya. This condition involves a deficiency in both the quality and quantity of Artava (menstrual blood and ovum), often resulting from the chronic accumulation of latent toxins, termed Dushi Visha. The current clinical investigation evaluates the efficacy of Maha Agad, a classical polyherbal formulation, in rectifying the underlying toxic pathology and restoring reproductive equilibrium in patients suffering from Dushi Visha Janya Artava Kshaya.
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