“Prevalence Of Metabolic Syndrome In Alcohol Dependence: A Cross Sectional Study In Patients Coming To A Tertiary Hospital”
DOI:
https://doi.org/10.69980/ajpr.v29i1.923Keywords:
Alcohol dependence syndrome; metabolic syndrome; AUDIT; cardiovascular risk; substance use disorders.Abstract
Background: Alcohol dependence syndrome (ADS) is associated with several physical health complications, including metabolic abnormalities. Metabolic syndrome (MS), characterized by central obesity, hypertension, dyslipidemia, and impaired glucose metabolism, increases the risk of cardiovascular disease and diabetes mellitus.
Aim: To determine the prevalence of metabolic syndrome among patients with alcohol dependence syndrome and to evaluate its clinical correlates.
Methods: This cross-sectional comparative study included 50 patients diagnosed with alcohol dependence syndrome and 50 age-matched non-alcohol-dependent controls attending a tertiary care hospital. Diagnosis of ADS was made using ICD-10 criteria. Severity of alcohol use was assessed using the Alcohol Use Disorders Identification Test (AUDIT). Metabolic syndrome was diagnosed using the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria.
Results: The mean age of patients with ADS was 38.9 ± 9.3 years, while that of controls was 36.9 ± 9.6 years. The prevalence of metabolic syndrome was 14% among patients with ADS compared with 4% among controls. Significant differences were observed between the groups in body mass index, waist circumference, and high-density lipoprotein cholesterol levels. Among patients with ADS, metabolic syndrome was significantly associated with body mass index, blood pressure, waist circumference, triglyceride levels, fasting blood glucose levels, and HDL cholesterol levels.
Conclusion: Metabolic syndrome is common among patients with alcohol dependence syndrome and occurs more frequently than in non-alcohol-dependent controls. Routine screening for metabolic abnormalities in patients with ADS may facilitate early intervention and help reduce future cardiovascular and metabolic complications.
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